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Osteopenia
These drugs have been linked to
the catastrophic condition(s) If you or a loved one has been taking any of these “Bisphosphonates”
for YOU MAY DESERVE COMPENSATION! Accepting Inquiries from the U.S. and Internationally Every case is different. No specific results are
implied.
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Osteopenia Information Osteopenia is defined as a bone density that is somewhat low. The World Health Organization formed a committee in 1994 to define bone mineral density disorders. That committee created four diagnostic categories: Normal, Osteopenia, Osteoporosis, and Established Osteoporosis. These diagnostic categories depend on the bone density, and the presence of fractures. The committee set cut-off values that were relative to young healthy individuals. The definitions involve "standard deviations" which are statistical units of variation. Osteopenia is a bone density between one standard deviation and 2.5 standard deviations below average for young people. Osteoporosis is a bone density lower than 2.5 standard deviations below young people. Established osteoporosis is a bone density lower than 2.5 standard deviations in the presence of fragility fractures. Bone density naturally declines with age in both men and women. The percentage of women who have osteopenia depends on age and race and use of hormones. By definition, 16% of white women aged 20-29 have osteopenia, and less than 1% have osteoporosis. Currently about 38% of women aged 65 have osteopenia and 20% have osteoporosis. By age 80 only 15% of women still have normal bone density, and those with osteopenia are above average for their age. The relationship between osteopenia and fractures depends heavily on age. In general, the risk of a fracture will double with every decade past 50, even with the same bone density. A woman aged 55 with osteopenia has about a 2% chance/year of having a fracture, and a woman aged 75 with osteopenia has about an 8% chance/year (which is approximately average for a 75 year-old woman). The lifetime risk of a hip fracture depends on age and bone density. A young person with osteopenia doesn't have much risk in the next 5 years, but if no prevention is done, the lifetime risk will be about 20 or 30%. An elderly woman with osteopenia has a lifetime risk of about 10%. Osteopenia and Osteoporosis in Men. This is a topic not often discussed, but nonetheless an issue to learn about and understand. In men over age 50 about 5 percent of all men have osteoporosis (7% in caucasians, 5% in blacks, and 3% in hispanics), and about 30-45% have osteopenia. Because men have a greater bone mass than women they generally develop osteoporosis at a later age than women - typically about age 75 when their incidence of hip fracture starts to increase. Men also have a much higher complication rate and death rate with fractures than women do - prevention is the key!! Risk Factors for Osteopenia and Osteoporosis. 1)
Long term glucocorticoids (prednisone, etc.) for asthma, inflammatory conditions like rheumatoid,
lupus, etc. are a major problem! Anyone on more than 5mg daily should be on
medication for prevention! 2) Seizure medications can lead to bone loss due to
effects on bone metabolism and Calcium and Vitamin D supplements are indicated.
3) Low levels of androgens in men and low levels of estrogens in women can lead
to bone density problems and hormone replacement for these specific conditions
are indicated with an understanding of the risks and benefits that this entails.
4) Hyperparathyroidism - this really affects bone density and needs evaluation
and treatment to preserve bone density! 5) Abnormal thyroid function, both under
and over function can adversely affect bone density. 6) Alcohol and Tobacco use
- the more you smoke or the more you drink, the more likely you are to have with
your bone density! 7) Low body weight - one of the few times a low weight is bad
for you - gravity pulling on your bones maintains your bone density - the less
you weigh, the less gravity pulls on your bones! 8) Lack of regular exercise -
similar reason as in #7 - the gravity pulling down on your bones as you exercise
preserves bone density - the best is jogging or running and running stairs - it
seems jarring type exercise is best, but any type of regular exercise helps! Although most cases of osteonecrosis of the jaw related to Fosamax side effects have occured after dental work several cases have been reported to occur without any prior dental work. If you are currently taking Fosamax,Zometa, and Aredia you may be at risk of developing osteonecrosis. If you have been injured by Fosamax,Zometa, and Aredia side effects you may be entitled to compensation. For more information about your legal rights contact the offices of Powell
Law Firm, L.C. Accepting Inquiries from the U.S. and Internationally Every case is different. No specific results are
implied. Accepting Inquiries from the U.S. and Internationally Every case is different. No specific results are
implied. Fosamax ( generic name - Alendronate ) is a type of drug known as bisphosphonates. Recently a link has been found between bisphosphonates and a serious bone cancer disease called osteonecrosis of the jaw ( ONJ ). This important discovery clearly shows that Fosamax side effects may include osteonecrosis of the jaw. The discovery, published in the Journal of Oral and Maxillofacial Surgeons, prompted both the US, Food and Drug Administration ( FDA ) and Novartis, the manufacturer of bisphosphonates used in cancer chemotherapy, to issue a warning to health care professionals on September 24, 2004. The warning letter contained information about jaw cancer and bisphosphonates and the risks of osteonecrosis in the jaw. Bisphosphonates are commonly used in tablet form such as Fosamax ( Alendronate Sodium ) to prevent and treat osteoporosis in post-menopausal women. Stronger forms of bisphosphonates are commonly used in the management of advanced cancers that have metastasized to the bone, where the disease often causes bone pain and possibly even fractures. Several cancers can involve or metastasize to the bone, including lung cancer, breast cancer, prostate cancer, multiple myeloma,jaw cancer, and others. When bisphosphonates are given in cancer chemotherapy, the drugs are given intravenously, and usually for longer periods of time.Although most cases of osteonecrosis of the jaw related to Fosamax side effects have occured after dental work several cases have been reported to occur without any prior dental work. If you are currently taking Fosamax,Zometa, and Aredia you may be at risk of developing osteonecrosis. If you have been injured by Fosamax,Zometa, and Aredia side effects you may be entitled to compensation. For more information about your legal rights contact the offices of Powell
Law Firm, L.C. Accepting Inquiries from the U.S. and Internationally Every case is different. No specific results are
implied.
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