Zometa Side Effects News
Urgent medical-dental alert for people who took
      
ZOMETA
®, FOSAMAX ®, or AREDIA ®

These drugs (Zometa, Fosamax, and Aredia)
have been linked to the catastrophic condition(s)
 “DEAD JAW” (Osteonecrosis of the jaw)
& other severe conditions

If you or a loved one has been taking any of these “Bisphosphonates”
for Osteoporosis, Cancer or Multiple Myeloma & you have
experienced complications, you must act now!

    YOU MAY DESERVE COMPENSATION!

Contact today the offices of

Powell Law Firm, L.C.
is the nation's leading law firm
for litigation regarding Bisphosphonate Complications
.

 
for your  free, confidential case evaluation
at toll-free 888-238-1998
Please state your name and phone number
And we will get back with you promptly

Accepting Inquiries from the U.S. and Internationally

Every case is different. No specific results are implied. 
 269 South Beverly Drive, Suite 1156, Beverly Hills, CA 90212

 
 
Zometa,Aredia and Fosamax News Article Links
 Fosamax and Zometa linked to jawbone death
 .or bone tumors. But about 10% were osteoporosis patients who had taken an oral bisphosphonate, mainly Fosamax. In May, Ruggiero ..News.
 Fosamax ,Aredia and Zometa causes Jaw Problems 
.News..given bisphosphonates intravenously. Some patients take oral bisphosphonates, such as Fosamax and Zometa, for osteoporosis. The FDA acknowledges ...
 Fosamax and Zometa Linked to Jaw Osteoporisis
 ..or Zoledronate/Zoledronic Acid ( Zometa ) therapy for malignancy, but several have occurred after oral treatment with Alendronate ( Fosamax,Zometa ) or Risedronate ... - Xagena.it
 

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Zometa,Aredia and Fosamax Information News

 Fosamax ( generic name - Alendronate ) and Zometa are types of drugs known as bisphosphonates. Recently a link has been found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw ( ONJ ). This important discovery clearly shows that Fosamax side effects may include osteonecrosis of the jaw.

The discovery, published in the Journal of Oral and Maxillofacial Surgeons, prompted both the US, Food and Drug Administration ( FDA ) and Novartis, the manufacturer of bisphosphonates used in cancer chemotherapy, to issue a warning to health care professionals on September 24, 2004. The warning letter contained information about bisphosphonates and the risks of osteonecrosis in the jaw.

Bisphosphonates are commonly used in tablet form such as Fosamax ( Alendronate Sodium ) to prevent and treat osteoporosis in post-menopausal women. Stronger forms of bisphosphonates are commonly used in the management of advanced cancers that have metastasized to the bone, where the disease often causes bone pain and possibly even fractures. Several cancers can involve or metastasize to the bone, including lung cancer, breast cancer, prostate cancer, multiple myeloma, and others. When bisphosphonates are given in cancer chemotherapy, the drugs are given intravenously, and usually for longer periods of time.

If you or a loved one have taken Fosamax or Zometa and have been injured as a result of Fosamax  or Zometa side effects such as osteonecrosis of the jaw contact today the offices of

Powell Law Firm, L.C.
is the nation's leading law firm
for litigation regarding Bisphosphonate Complications
.

 
for your  free, confidential case evaluation
at toll-free 888-238-1998
Please state your name and phone number
And we will get back with you promptly

Accepting Inquiries from the U.S. and Internationally

Every case is different. No specific results are implied. 
 269 South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
.
.

Osteonecrosis of the Jaw
Osteonecrosis of the jaw ( ONJ ) is a condition in which the bone tissue in the jaw fails to heal after minor trauma such as a tooth extraction, causing the bone to be exposed. The exposure can eventually lead to infection and fracture and may require long-term antibiotic therapy or surgery to remove the dying bone tissue. Experts say that prevention and early treatment of individuals using bisphosphonates such as Fosamax or Zometa is extremely important in preserving the jaw bone. Individuals using Fosomax, Zometa or other bisphosphonates should attempt to avoid tooth extractions and other major dental work while on the drugs.

Although most cases of osteonecrosis of the jaw related to Fosamax or Zometa side effects have occured after dental work several cases have been reported to occur without any prior dental work. If you are currently taking Fosamax or Zometa you may be at risk of developing osteonecrosis. If you have been injured by Fosamax or Zometa side effects you may be entitled to compensation. For more information about your legal rights contact the offices of

Powell Law Firm, L.C.
is the nation's leading law firm
for litigation regarding Bisphosphonate Complications
.

 
for your  free, confidential case evaluation
at toll-free 888-238-1998
Please state your name and phone number
And we will get back with you promptly

Accepting Inquiries from the U.S. and Internationally

Every case is different. No specific results are implied. 
 269 South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
 

Zometa News Articles

 IMF: Aredia and Zometa and osteonecrosis of the jaws A New Update ...

... finding was the apparent occurrence of jaw osteonecrosis in patients taking bisphosphonates. ... How common is jaw osteonecrosis in myeloma patients? ...
www.myeloma.org/main.jsp?type=article& tab_id=1&menu_id=0&id=1259 - 50k - Cached - Similar pages

 ADRAC : bisphosphonates and osteonecrosis of the jaw Open this result in new window

Medicine - Medicine News Xagena ... treatment, osteonecrosis of the jaw, has been described in ... Zoledronate/Zoledronic Acid ( Zometa ) therapy for malignancy, but ... Presentation includes jaw pain, toothache, exposed bone ...
xagena.it/news/..

ABC News: Novartis Sees Jaw Damage in Cancer Drug Patients

... Novartis AG has received 875 reports of jaw problems in patients treated with two cancer drugs, but it ... sign the cases were related to the drugs, Zometa and Aredia. FDA officials urged further study to ...

  • abcnews.go.com/Health/wireStory?id=552022

 http://www.bethesda.med.navy.mil/careers/postgraduate_dental_school/research/clinical_updates/2005/0... (MICROSOFT WORD) Open this result in new window

... Aredia®, Novartis, East Hanover, NJ), zolendronate (Zometa®, Novartis, East Hanover, NJ), and alendronate (Fosamax ... JW, Marek CL. Bis-phossy jaw, phossy jaw, and the 21st century ...
bethesda.med.navy.mil/careers/postgraduate_dental_school/research/

Osteoporosis Therapy Resources Open this result in new window
... onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, according to an ...
bestmedicalid.com/resources/osteoporosis/4/osteoporosis-therapy.html
 
Bisphosphonates Can Wreak Havoc in the Mouth and Jaws, Oral and Maxillofacial Surgeon Warns Open this result in new window
... onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, according ... increase the risk of bis-phossy jaw, it is the injectable medications ...
biz.yahoo.com/prnews/050505/cgth062.html?.v=9

MedWatch - 2005 Safety Information Alerts

... Report | Contact MedWatch Zometa (zoledronic acid) Aredia ... of osteonecrosis of the jaw (ONJ) observed in cancer patients ... disorders. Mislabeling problems with certain lots of this product ...

... onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, according ... increase the risk of bis-phossy jaw, it is the injectable medications ...
www.hkstp.org/english/news/news_health/news_health_read.php?id=142972
mysan.de - be updated - Bisphosphonates Can Wreak Havoc in the Mouth and Jaws, Oral and Maxillofacial Surgeon Warns Open this result in new window
mysan.de is a newsportal with english and german news. ... onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, according ... increase the risk of bis-phossy jaw, it is the injectable medications ...
www.mysan.de/article97803.html

Últimas novedades por revista Open this result in new window
... Bisphosphonate Osteochemonecrosis (Bis-Phossy Jaw): Is This Phossy Jaw of the 21st Century? ... Oral and Maxillofacial Surgery. Conclusion: Bis-phossy jaw may have more of a bacterial ...
www.lasalud.com/busquedas/buscar_por_revista.htm?revi=1323

Drug Topics - Hot Off The Press Open this result in new window
... to the onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition ... increase the risk of bis-phossy jaw, the injectable medications appear to ...
www.drugtopics.com/drugtopics/static/staticHtml.jsp?id=86717

Surgery Press Releases Open this result in new window
... of metastatic cancer may actually contribute to the onset of osteochemonecrosis, or "bis-phossy ... named Katie underwent orthognathic surgery to correct a protruding jaw in January ...
rss.topix.net/med/surgery/pr

Health - Oral Health Open this result in new window
Health - Oral Health Articles and Resources. ... onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, according to an ...
www.www--health.com/oralhealth

Dental Amalgam and Mercury Open this result in new window
... and maxilla, is also called Phossy Jaw or Maxillofacial Osteonecrosis ... the pre-antibiotic era "phossy jaw" and other forms of ... osteomyelitis described in Phossy Jaw can be seen in ...
www.stanford.edu/~bcalhoun/amalgam.htm

FOX5 Las Vegas - Bisphosphonates Can Wreak Havoc in the Mouth and ...
Bis-phossy jaw warrants the attention of oral and maxillofacial surgeons (OMSs) and other health care professionals in part because bisphosphonate therapy ...
www.kvvu.com/Global/story.asp?S=3305846
 
bisphosphonates
Bisphosphonate osteochemonecrosis (bis-phossy jaw): is this phossy jaw of the 21st century? J Oral Maxillofac Surg. 2005 May;63(5):682-9. ...
www.dentalgentlecare.com/biop.htm
 
Entrez PubMed
RESULTS: Descriptions of phossy jaw and current bis-phossy jaw cases are remarkably ... Histopathologic features of bis-phossy jaw showed intact vascular ...
www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search& doptcmdl=Abstract&db=PubMed&orig_db=PubMed&
 
Journal of Oral and Maxillofacial Surgery, 2005; 63 (5)
Bisphosphonate Osteochemonecrosis (Bis-Phossy Jaw): Is This Phossy Jaw of the 21st Century? / Hellstein, John W / Marek, Cindy L, 682-689 ...
www.ucm.es/BUCM/compludoc/W/10505/02782391_2.htm
 
College of Pharmacy - University of Iowa
Bis-phossy jaw, Phosy Jaw and the 21st Century: Bisphosphonate Associated Complications of the Jaws.” The Journal of Oral and Maxillofacial Surgery 62( 12): ...
pharmacy.uiowa.edu/new/pharmreport/publications.htm
 

Surgery Press Releases
... may actually contribute to the onset of osteochemonecrosis, or "bis-phossy . ... underwent orthognathic surgery to correct a protruding jaw in January. ...
www.topix.net/med/surgery/pr

american association of oral maxillofacial surgery
... of metastatic cancer may actually contribute to the onset of osteochemonecrosis, or "bis-phossy jaw," a painful, potentially disfiguring jaw condition, ...
surgery.advicepoint.net/ american-association-of-oral-maxillofacial-surgery/index.php


 

 Novartis Q4 misses forecasts, but R&D pleases  Jan 20, 2005
Pharma sales in 2004 were lifted by its Diovan hypertension medication, Gleevec leukemia drug, Lamisil nail infection drug, Zometa intravenous treatment for ... - Investor's Business Daily (subscription)

 Improved Dosing Regimens and Novel Mechanisms of Action Drive ...  Jan 18, 2005
...effective in managing osteoporosis, the introduction of bisphosphonates with monthly and yearly dosing regimens in the form of Boniva and Zometa is likely to ... - Business Wire (press release),

Schering Cancer Drug Faces US Delay  Jan 7, 2005
Novartis's rival product Zometa, for example, had sales of nearly $900 million in 2003, of which two-thirds was in the United States. - MSN Money

New Clinical Trial Initiated to Evaluate QUADRAMET(R) in ...  Jan 11, 2005
...from a single arm phase II trial conducted by independent investigators in Europe that evaluated the efficacy of QUADRAMET and zoledronic acid (Zometa(R) by ... - ArriveNet (press release),

Doctors Link Common Chemotherapy Drug To Jawbone Necrosis  Dec 30, 2004
December 16, 2004) -- Novartis has notified healthcare professionals about new precautions for the company's two bisphosphonate drugs, Zometa (zoledronic acid ... - Science Daily (press release)


NEW STUDY RESULTS SHOW ABILITY OF ZOMETA TO DELAY ONSET OF ...   Sep 1, 2003
Novartis AG’s Zometa (zoledronic acid) demonstrated significant clinical benefit in a placebo-controlled study published in the Sept. 1 issue of Cancer. ... (Pharmexec (press release))

Novartis: bisphosphonate study should boost Zometa sales  Sep 2, 2003
With Novartis' [NVS] Zometa recently gaining a sNDA for patients with bone metastases from advanced malignancies and this class of adjunct therapy becoming ... (UK Comment Wire, UK)

Community hospitals enter field of drug trials  Sep 15, 2003
Zometa, a second drug in the study, is being tested for its effectiveness in preventing osteoporosis in women taking hormone blockers. ... (Arkansas Democrat Gazette, AR)

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